SEPHA






All machines in the EZ BLISTER range are ideal for stability batches and clinical trials
Save R&D time and costs
Reduce delays to a minimum
Can be operated by unskilled staff
Earn earlier profits as new products get to market faster

"The estimated cost of one day's delay in the development of a new drug is about US$1.3 million"

Flexibility:
It is important that a blisterpacker used for stability studies and pack development can produce packs from a wide variety of materials on the market. This is why EZ BLISTER machines handle both thermoforming materials such as PVC, PVDC, PP and Aclar, and cold-form materials like Alu/Alu. They can also produce the extra large blister cards required for some clinical trial packs.

Flexibility in blister design is also essential for R&D or marketing samples. This might include novel format shapes, perforations, or even tropicalised blisters. With EZ BLISTER machines this flexibility is available, in your lab, every day.

Compact but Multi-Functional:
EZ BLISTER machines are designed to offer as many blisterpacking options as possible within in a single, small, mobile unit. Blisters are formed, cut and sealed at the same station which can be easily installed at the end of any lab bench.

Blisterpack Design Assistance:
We understand that you may need assistance and advice on the design of your new blisterpack. Sepha can offer advice and assistance about the materials which can be used to give adequate protection to various products. We can design the most suitable blisters to make the most economic use of your tooling format. Often an R&D department must package drugs of many different sizes and shapes for different projects. Sepha can help you to rationalise your blister designs to reduce the number of different tooling sets required, thus minimising spending.

Fast Turnaround for New Tooling - You Control Your R&D Schedule:
Thermoform tooling for EZ BLISTER machines can be delivered in 2-3 weeks and cold-form tooling is turned around in 6-8 weeks. This is a very short lead time, compared with the length of time it can take to outsource small batches to a contract packer.

Easy to Set-up and Use:
We do not expect EZ BLISTER users to have engineering training. That is why we have de-skilled EZ BLISTER machines so they are easy for non-technical staff to use. We have even built in and patented quick-release mechanisms so that the operator can switch changeparts for a different blister format within a matter of seconds. This means no extra hand-tools are required during changeover.

Highest Quality Blisterpacks:
For accurate testing, R&D must produce blisterpacks which are of the same high quality as blisters produced on the high speed packaging lines used in full-scale production. Therefore, R&D need to use the same blisterpacking techniques, materials and parameters.

The results achieved on production machines can be reproduced on EZ BLISTER machines because the operator can electronically control the temperature, dwell-time and air pressure parameters required to make the blisterpack. R&D can use the same parameters as those used on production equipment.

The quality of seal produced on EZ BLISTER machines is also identical to the platen seals produced on larger packaging lines. It is important that drugs issued to clinical trial patients have the same level of packaging protection as they would have if the drug was in full-scale production for sale on the market. Generally, the quality of packs produced on the cheaper machines is unsuitable for stability or clinical studies. The method of operation of these cheaper machines does not imitate the methods used by production machines so the results obtained are of no use in the development of products for the market.

SEPHA continually develops innovative ways to make life easier for R&D departments within the pharmaceutical industry. Contact us to find out how you can benefit.


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